diff --git a/conda/artiq-dev/meta.yaml b/conda/artiq-dev/meta.yaml
index 95c68d325..d3ff8b169 100644
--- a/conda/artiq-dev/meta.yaml
+++ b/conda/artiq-dev/meta.yaml
@@ -12,7 +12,7 @@ build:
 
 requirements:
   run:
-    - python >=3.5.2,<3.6
+    - python >=3.5.3,<3.6
     - setuptools
     - migen 0.5.dev py_57+gitd4afdeb
     - misoc 0.6.dev py_17+git2d3f62f
diff --git a/conda/artiq-doc.yaml b/conda/artiq-doc.yaml
index a51c2e18b..fda3c11ba 100644
--- a/conda/artiq-doc.yaml
+++ b/conda/artiq-doc.yaml
@@ -6,7 +6,7 @@ channels:
   - m-labs/label/main
   - defaults
 dependencies:
-  - python>=3.5.2,<3.6
+  - python>=3.5.3,<3.6
   - sphinx=1.4.8
   - sphinx-argparse
   - sphinxcontrib-wavedrom
diff --git a/conda/artiq/meta.yaml b/conda/artiq/meta.yaml
index c133f4ef5..5cdafa2db 100644
--- a/conda/artiq/meta.yaml
+++ b/conda/artiq/meta.yaml
@@ -12,10 +12,10 @@ build:
 
 requirements:
   build:
-    - python >=3.5.2,<3.6
+    - python >=3.5.3,<3.6
     - setuptools
   run:
-    - python >=3.5.2,<3.6
+    - python >=3.5.3,<3.6
     - llvmlite-artiq 0.12.0.dev py35_30
     - binutils-or1k-linux
     - pythonparser 1.0
diff --git a/setup.py b/setup.py
index 94042d905..a9ad48dcc 100755
--- a/setup.py
+++ b/setup.py
@@ -7,8 +7,8 @@ import fastentrypoints
 import versioneer
 
 
-if not (3, 5, 2) <= sys.version_info[:3] < (3, 6, 0):
-    raise Exception("You need Python 3.5.2+")
+if not (3, 5, 3) <= sys.version_info[:3] < (3, 6, 0):
+    raise Exception("You need Python 3.5.3+ (but not 3.6+)")
 
 
 # Depends on PyQt5, but setuptools cannot check for it.