diff --git a/artiq/coredevice/core.py b/artiq/coredevice/core.py
index 0cdd1bd43..2b362f604 100644
--- a/artiq/coredevice/core.py
+++ b/artiq/coredevice/core.py
@@ -2,6 +2,7 @@ import os
 
 from artiq.transforms.inline import inline
 from artiq.transforms.lower_units import lower_units
+from artiq.transforms.remove_inter_assigns import remove_inter_assigns
 from artiq.transforms.fold_constants import fold_constants
 from artiq.transforms.unroll_loops import unroll_loops
 from artiq.transforms.interleave import interleave
@@ -51,6 +52,9 @@ class Core:
         lower_units(func_def, rpc_map)
         _debug_unparse("lower_units", func_def)
 
+        remove_inter_assigns(func_def)
+        _debug_unparse("remove_inter_assigns_1", func_def)
+
         fold_constants(func_def)
         _debug_unparse("fold_constants_1", func_def)
 
@@ -65,6 +69,9 @@ class Core:
                    self.runtime_env.ref_period)
         _debug_unparse("lower_time", func_def)
 
+        remove_inter_assigns(func_def)
+        _debug_unparse("remove_inter_assigns_2", func_def)
+
         fold_constants(func_def)
         _debug_unparse("fold_constants_2", func_def)
 
diff --git a/artiq/transforms/remove_inter_assigns.py b/artiq/transforms/remove_inter_assigns.py
new file mode 100644
index 000000000..4479e116c
--- /dev/null
+++ b/artiq/transforms/remove_inter_assigns.py
@@ -0,0 +1,145 @@
+import ast
+from copy import copy, deepcopy
+
+
+_replaceable_funcs = {
+    "bool", "int", "float", "round",
+    "int64", "round64", "Fraction",
+}
+
+
+def _is_replaceable(value):
+    if isinstance(value, (ast.NameConstant, ast.Num, ast.Str)):
+        return True
+    elif isinstance(value, ast.BinOp):
+        return _is_replaceable(value.left) and _is_replaceable(value.right)
+    elif isinstance(value, ast.BoolOp):
+        return all(_is_replaceable(v) for v in value.values)
+    elif isinstance(value, ast.Call) and isinstance(value.func, ast.Name):
+        return value.func.id in _replaceable_funcs
+    else:
+        return False
+
+
+class _TargetLister(ast.NodeVisitor):
+    def __init__(self):
+        self.targets = set()
+
+    def visit_Name(self, node):
+        if isinstance(node.ctx, ast.Store):
+            self.targets.add(node.id)
+
+
+class _InterAssignRemover(ast.NodeTransformer):
+    def __init__(self):
+        self.replacements = dict()
+        self.modified_names = set()
+
+    def visit_Name(self, node):
+        if isinstance(node.ctx, ast.Load):
+            try:
+                return self.replacements[node.id]
+            except KeyError:
+                return node
+        else:
+            self.modified_names.add(node.id)
+            return node
+
+    def visit_Assign(self, node):
+        self.generic_visit(node)
+        if _is_replaceable(node.value):
+            for target in node.targets:
+                if isinstance(target, ast.Name):
+                    self.replacements[target.id] = node.value
+        else:
+            for target in node.targets:
+                try:
+                    del self.replacements[target.id]
+                except KeyError:
+                    pass
+        return node
+
+    def visit_AugAssign(self, node):
+        left = deepcopy(node.target)
+        left.ctx = ast.Load()
+        newnode = ast.copy_location(
+            ast.Assign(
+                targets=[node.target],
+                value=ast.BinOp(left=left, op=node.op, right=node.value)
+            ),
+            node
+        )
+        return self.visit_Assign(newnode)
+
+    def modified_names_push(self):
+        prev_modified_names = self.modified_names
+        self.modified_names = set()
+        return prev_modified_names
+
+    def modified_names_pop(self, prev_modified_names):
+        for name in self.modified_names:
+            try:
+                del self.replacements[name]
+            except KeyError:
+                pass
+        self.modified_names |= prev_modified_names
+
+    def visit_Try(self, node):
+        prev_modified_names = self.modified_names_push()
+        self.generic_visit(node)
+        self.modified_names_pop(prev_modified_names)
+        return node
+
+    def visit_If(self, node):
+        node.test = self.visit(node.test)
+
+        prev_modified_names = self.modified_names_push()
+
+        prev_replacements = self.replacements
+        self.replacements = copy(prev_replacements)
+        node.body = [self.visit(n) for n in node.body]
+        self.replacements = copy(prev_replacements)
+        node.orelse = [self.visit(n) for n in node.orelse]
+        self.replacements = prev_replacements
+
+        self.modified_names_pop(prev_modified_names)
+
+        return node
+
+    def visit_loop(self, node):
+        prev_modified_names = self.modified_names_push()
+        prev_replacements = self.replacements
+
+        self.replacements = copy(prev_replacements)
+        tl = _TargetLister()
+        for n in node.body:
+            tl.visit(n)
+        for name in tl.targets:
+            try:
+                del self.replacements[name]
+            except KeyError:
+                pass
+        node.body = [self.visit(n) for n in node.body]
+
+        self.replacements = copy(prev_replacements)
+        node.orelse = [self.visit(n) for n in node.orelse]
+
+        self.replacements = prev_replacements
+        self.modified_names_pop(prev_modified_names)
+
+    def visit_For(self, node):
+        prev_modified_names = self.modified_names_push()
+        node.target = self.visit(node.target)
+        self.modified_names_pop(prev_modified_names)
+        node.iter = self.visit(node.iter)
+        self.visit_loop(node)
+        return node
+
+    def visit_While(self, node):
+        self.visit_loop(node)
+        node.test = self.visit(node.test)
+        return node
+
+
+def remove_inter_assigns(func_def):
+    _InterAssignRemover().visit(func_def)