diff --git a/artiq/examples/kasli_basic/device_db_ptb2.py b/artiq/examples/kasli_basic/device_db_ptb2.py
new file mode 100644
index 000000000..ed6d4722f
--- /dev/null
+++ b/artiq/examples/kasli_basic/device_db_ptb2.py
@@ -0,0 +1,240 @@
+core_addr = "staging.ber.quartiq.de"
+
+device_db = {
+    "core": {
+        "type": "local",
+        "module": "artiq.coredevice.core",
+        "class": "Core",
+        "arguments": {"host": core_addr, "ref_period": 1e-9}
+    },
+    "core_log": {
+        "type": "controller",
+        "host": "::1",
+        "port": 1068,
+        "command": "aqctl_corelog -p {port} --bind {bind} " + core_addr
+    },
+    "core_cache": {
+        "type": "local",
+        "module": "artiq.coredevice.cache",
+        "class": "CoreCache"
+    },
+    "core_dma": {
+        "type": "local",
+        "module": "artiq.coredevice.dma",
+        "class": "CoreDMA"
+    },
+
+    "i2c_switch0": {
+        "type": "local",
+        "module": "artiq.coredevice.i2c",
+        "class": "PCA9548",
+        "arguments": {"address": 0xe0}
+    },
+    "i2c_switch1": {
+        "type": "local",
+        "module": "artiq.coredevice.i2c",
+        "class": "PCA9548",
+        "arguments": {"address": 0xe2}
+    },
+}
+
+
+device_db.update({
+    "ttl" + str(i): {
+        "type": "local",
+        "module": "artiq.coredevice.ttl",
+        "class": "TTLInOut" if i < 4 else "TTLOut",
+        "arguments": {"channel": i},
+    } for i in range(24)
+})
+
+
+device_db.update({
+    "spi_sampler0_adc": {
+        "type": "local",
+        "module": "artiq.coredevice.spi2",
+        "class": "SPIMaster",
+        "arguments": {"channel": 24}
+    },
+    "spi_sampler0_pgia": {
+        "type": "local",
+        "module": "artiq.coredevice.spi2",
+        "class": "SPIMaster",
+        "arguments": {"channel": 25}
+    },
+    "spi_sampler0_cnv": {
+        "type": "local",
+        "module": "artiq.coredevice.ttl",
+        "class": "TTLOut",
+        "arguments": {"channel": 26},
+    },
+    "sampler0": {
+        "type": "local",
+        "module": "artiq.coredevice.sampler",
+        "class": "Sampler",
+        "arguments": {
+            "spi_adc_device": "spi_sampler0_adc",
+            "spi_pgia_device": "spi_sampler0_pgia",
+            "cnv_device": "spi_sampler0_cnv"
+        }
+    }
+})
+
+device_db.update({
+    "spi_urukul0": {
+        "type": "local",
+        "module": "artiq.coredevice.spi2",
+        "class": "SPIMaster",
+        "arguments": {"channel": 27}
+    },
+    "ttl_urukul0_io_update": {
+        "type": "local",
+        "module": "artiq.coredevice.ttl",
+        "class": "TTLOut",
+        "arguments": {"channel": 28}
+    },
+    "ttl_urukul0_sw0": {
+        "type": "local",
+        "module": "artiq.coredevice.ttl",
+        "class": "TTLOut",
+        "arguments": {"channel": 29}
+    },
+    "ttl_urukul0_sw1": {
+        "type": "local",
+        "module": "artiq.coredevice.ttl",
+        "class": "TTLOut",
+        "arguments": {"channel": 30}
+    },
+    "ttl_urukul0_sw2": {
+        "type": "local",
+        "module": "artiq.coredevice.ttl",
+        "class": "TTLOut",
+        "arguments": {"channel": 31}
+    },
+    "ttl_urukul0_sw3": {
+        "type": "local",
+        "module": "artiq.coredevice.ttl",
+        "class": "TTLOut",
+        "arguments": {"channel": 32}
+    },
+    "urukul0_cpld": {
+        "type": "local",
+        "module": "artiq.coredevice.urukul",
+        "class": "CPLD",
+        "arguments": {
+            "spi_device": "spi_urukul0",
+            "io_update_device": "ttl_urukul0_io_update",
+            "refclk": 100e6,
+            "clk_sel": 0
+        }
+    }
+})
+
+device_db.update({
+    "urukul0_ch" + str(i): {
+        "type": "local",
+        "module": "artiq.coredevice.ad9912",
+        "class": "AD9912",
+        "arguments": {
+            "pll_n": 10,
+            "chip_select": 4 + i,
+            "cpld_device": "urukul0_cpld",
+            "sw_device": "ttl_urukul0_sw" + str(i)
+        }
+    } for i in range(4)
+})
+
+
+device_db.update({
+    "spi_urukul1": {
+        "type": "local",
+        "module": "artiq.coredevice.spi2",
+        "class": "SPIMaster",
+        "arguments": {"channel": 33}
+    },
+    "ttl_urukul1_sync": {
+        "type": "local",
+        "module": "artiq.coredevice.ttl",
+        "class": "TTLClockGen",
+        "arguments": {"channel": 34, "acc_width": 4}
+    },
+    "ttl_urukul1_io_update": {
+        "type": "local",
+        "module": "artiq.coredevice.ttl",
+        "class": "TTLOut",
+        "arguments": {"channel": 35}
+    },
+    "urukul1_cpld": {
+        "type": "local",
+        "module": "artiq.coredevice.urukul",
+        "class": "CPLD",
+        "arguments": {
+            "spi_device": "spi_urukul1",
+            "sync_device": "ttl_urukul1_sync",
+            "io_update_device": "ttl_urukul1_io_update",
+            "refclk": 125e6,
+            "clk_sel": 0
+        }
+    }
+})
+
+device_db.update({
+    "urukul1_ch" + str(i): {
+        "type": "local",
+        "module": "artiq.coredevice.ad9910",
+        "class": "AD9910",
+        "arguments": {
+            "pll_n": 32,
+            "chip_select": 4 + i,
+            "cpld_device": "urukul1_cpld"
+        }
+    } for i in range(4)
+})
+
+
+device_db.update({
+    "led0": {
+        "type": "local",
+        "module": "artiq.coredevice.ttl",
+        "class": "TTLOut",
+        "arguments": {"channel": 36}
+    },
+    "led1": {
+        "type": "local",
+        "module": "artiq.coredevice.ttl",
+        "class": "TTLOut",
+        "arguments": {"channel": 37}
+    }
+})
+
+
+device_db.update({
+    "spi_zotino0": {
+        "type": "local",
+        "module": "artiq.coredevice.spi2",
+        "class": "SPIMaster",
+        "arguments": {"channel": 38}
+    },
+    "ttl_zotino0_ldac": {
+        "type": "local",
+        "module": "artiq.coredevice.ttl",
+        "class": "TTLOut",
+        "arguments": {"channel": 39}
+    },
+    "ttl_zotino0_clr": {
+        "type": "local",
+        "module": "artiq.coredevice.ttl",
+        "class": "TTLOut",
+        "arguments": {"channel": 40}
+    },
+    "zotino0": {
+        "type": "local",
+        "module": "artiq.coredevice.zotino",
+        "class": "Zotino",
+        "arguments": {
+            "spi_device": "spi_zotino0",
+            "ldac_device": "ttl_zotino0_ldac",
+            "clr_device": "ttl_zotino0_clr"
+        }
+    }
+})
diff --git a/artiq/gateware/targets/kasli.py b/artiq/gateware/targets/kasli.py
index 60b7b0af1..61191e963 100755
--- a/artiq/gateware/targets/kasli.py
+++ b/artiq/gateware/targets/kasli.py
@@ -535,6 +535,47 @@ class PTB(_StandaloneBase):
         self.add_rtio(self.rtio_channels)
 
 
+class PTB2(_StandaloneBase):
+    """PTB Kasli variant with Urukul1 SYNC and external reference clock"""
+    def __init__(self, hw_rev=None, **kwargs):
+        if hw_rev is None:
+            hw_rev = "v1.1"
+        _StandaloneBase.__init__(self, hw_rev=hw_rev, **kwargs)
+
+        self.config["SI5324_AS_SYNTHESIZER"] = None
+        self.config["SI5324_EXT_REF"] = None
+        self.config["RTIO_FREQUENCY"] = "125.0"
+        if hw_rev == "v1.0":
+            # EEM clock fan-out from Si5324, not MMCX
+            self.comb += self.platform.request("clk_sel").eq(1)
+
+        self.rtio_channels = []
+        eem.DIO.add_std(self, 0,
+            ttl_serdes_7series.InOut_8X, ttl_serdes_7series.Output_8X)
+        eem.DIO.add_std(self, 1,
+            ttl_serdes_7series.Output_8X, ttl_serdes_7series.Output_8X)
+        eem.DIO.add_std(self, 2,
+            ttl_serdes_7series.Output_8X, ttl_serdes_7series.Output_8X)
+        eem.Sampler.add_std(self, 3, None, ttl_serdes_7series.Output_8X)
+        eem.Urukul.add_std(self, 5, 4, ttl_serdes_7series.Output_8X)
+        eem.Urukul.add_std(self, 6, None, ttl_serdes_7series.Output_8X,
+                           ttl_simple.ClockGen)
+
+        for i in (1, 2):
+            sfp_ctl = self.platform.request("sfp_ctl", i)
+            phy = ttl_simple.Output(sfp_ctl.led)
+            self.submodules += phy
+            self.rtio_channels.append(rtio.Channel.from_phy(phy))
+
+        eem.Zotino.add_std(self, 7, ttl_serdes_7series.Output_8X)
+
+        self.config["HAS_RTIO_LOG"] = None
+        self.config["RTIO_LOG_CHANNEL"] = len(self.rtio_channels)
+        self.rtio_channels.append(rtio.LogChannel())
+
+        self.add_rtio(self.rtio_channels)
+
+
 class HUB(_StandaloneBase):
     """HUB Kasli variant
 
@@ -1047,7 +1088,8 @@ def main():
     soc_kasli_args(parser)
     parser.set_defaults(output_dir="artiq_kasli")
     variants = {cls.__name__.lower(): cls for cls in [
-        Opticlock, SUServo, SYSU, MITLL, MITLL2, USTC, Tsinghua, WIPM, NUDT, PTB, HUB, LUH,
+        Opticlock, SUServo, PTB, PTB2, HUB, LUH,
+        SYSU, MITLL, MITLL2, USTC, Tsinghua, WIPM, NUDT,
         VLBAIMaster, VLBAISatellite, Tester, Master, Satellite]}
     parser.add_argument("-V", "--variant", default="opticlock",
                         help="variant: {} (default: %(default)s)".format(