diff --git a/conda/artiq-dev/meta.yaml b/conda/artiq-dev/meta.yaml
index 5817fd27b..4e1a02131 100644
--- a/conda/artiq-dev/meta.yaml
+++ b/conda/artiq-dev/meta.yaml
@@ -29,7 +29,6 @@ requirements:
     - scipy
     - numpy
     - prettytable
-    - asyncserial
     - sphinx 1.4.8
     - sphinx-argparse
     - sphinxcontrib-wavedrom
diff --git a/conda/artiq/meta.yaml b/conda/artiq/meta.yaml
index 31cf6bf4a..2c17fd2e4 100644
--- a/conda/artiq/meta.yaml
+++ b/conda/artiq/meta.yaml
@@ -35,7 +35,6 @@ requirements:
     - scipy
     - numpy
     - prettytable
-    - asyncserial
     - h5py 2.8
     - python-dateutil
     - pyqt >=5.5
diff --git a/doc/manual/conf.py b/doc/manual/conf.py
index 262ea2b88..db73a32e8 100644
--- a/doc/manual/conf.py
+++ b/doc/manual/conf.py
@@ -32,7 +32,7 @@ mock_modules = ["artiq.gui.waitingspinnerwidget",
                 "artiq.compiler.embedding",
                 "quamash", "pyqtgraph", "matplotlib",
                 "numpy", "dateutil", "dateutil.parser", "prettytable", "PyQt5",
-                "h5py", "serial", "scipy", "scipy.interpolate", "asyncserial",
+                "h5py", "serial", "scipy", "scipy.interpolate",
                 "llvmlite_artiq", "Levenshtein", "aiohttp", "pythonparser"]
 
 for module in mock_modules:
diff --git a/setup.py b/setup.py
index f57925539..fbfc34ea1 100755
--- a/setup.py
+++ b/setup.py
@@ -12,7 +12,7 @@ if sys.version_info[:3] < (3, 5, 3):
 
 # Depends on PyQt5, but setuptools cannot check for it.
 requirements = [
-    "asyncserial", "numpy", "scipy",
+    "numpy", "scipy",
     "python-dateutil", "prettytable", "h5py",
     "quamash", "pyqtgraph", "pygit2", "aiohttp",
     "llvmlite_artiq", "pythonparser", "python-Levenshtein",