diff --git a/artiq/coredevice/dds.py b/artiq/coredevice/dds.py
index fc9952980..9332ac34c 100644
--- a/artiq/coredevice/dds.py
+++ b/artiq/coredevice/dds.py
@@ -14,6 +14,11 @@ PHASE_MODE_TRACKING = 2
 def dds_init(time_mu: TInt64, bus_channel: TInt32, channel: TInt32) -> TNone:
     raise NotImplementedError("syscall not simulated")
 
+@syscall(flags={"nowrite"})
+def dds_init_sync(time_mu: TInt64, bus_channel: TInt32,
+                  channel: TInt32, sync_delay: TInt32) -> TNone:
+    raise NotImplementedError("syscall not simulated")
+
 @syscall(flags={"nowrite"})
 def dds_set(time_mu: TInt64, bus_channel: TInt32, channel: TInt32, ftw: TInt32,
             pow: TInt32, phase_mode: TInt32, amplitude: TInt32) -> TNone:
@@ -151,6 +156,24 @@ class _DDSGeneric:
         timing margin."""
         dds_init(now_mu(), self.bus_channel, self.channel)
 
+    @kernel
+    def init_sync(self, sync_delay=0):
+        """Resets and initializes the DDS channel as well as configures
+        the AD9914 DDS for synchronisation. The synchronisation procedure
+        follows the steps outlined in the AN-1254 application note.
+
+        This needs to be done for each DDS channel before it can be used, and
+        it is recommended to use the startup kernel for this.
+
+        This function cannot be used in a batch; the correct way of
+        initializing multiple DDS channels is to call this function
+        sequentially with a delay between the calls. 10ms provides a good
+        timing margin.
+
+        :param sync_delay: integer from 0 to 0x3f that sets value of
+        SYNC_OUT (bits 3-5) and SYNC_IN (bits 0-2) delay ADJ bits."""
+        dds_init_sync(now_mu(), self.bus_channel, self.channel, sync_delay)
+
     @kernel
     def set_phase_mode(self, phase_mode):
         """Sets the phase mode of the DDS channel. Supported phase modes are:
diff --git a/artiq/runtime/dds.c b/artiq/runtime/dds.c
index 44661658c..4f882aacb 100644
--- a/artiq/runtime/dds.c
+++ b/artiq/runtime/dds.c
@@ -22,6 +22,7 @@
 #define DURATION_DAC_CAL (147000 << CONFIG_RTIO_FINE_TS_WIDTH)
 /* not counting final FUD */
 #define DURATION_INIT (8*DURATION_WRITE + DURATION_DAC_CAL)
+#define DURATION_INIT_SYNC (16*DURATION_WRITE + 2*DURATION_DAC_CAL)
 #define DURATION_PROGRAM (6*DURATION_WRITE) /* not counting FUD */
 
 #else
@@ -83,6 +84,41 @@ void dds_init(long long int timestamp, int bus_channel, int channel)
 #endif
 }
 
+void dds_init_sync(long long int timestamp, int bus_channel, int channel, int sync_delay)
+{
+    long long int now;
+
+    now = timestamp - DURATION_INIT_SYNC;
+
+#ifdef CONFIG_DDS_ONEHOT_SEL
+    channel = 1 << channel;
+#endif
+    channel <<= 1;
+    DDS_WRITE(DDS_GPIO, channel);
+
+#ifdef CONFIG_DDS_AD9914
+    DDS_WRITE(DDS_CFR4H, 0x0105); /* Enable DAC calibration */
+    DDS_WRITE(DDS_FUD, 0);
+    now += DURATION_DAC_CAL;
+    DDS_WRITE(DDS_CFR4H, 0x0005); /* Disable DAC calibration */
+    DDS_WRITE(DDS_FUD, 0);
+    DDS_WRITE(DDS_CFR2L, 0x8b00); /* Enable matched latency and sync_out*/
+    DDS_WRITE(DDS_FUD, 0);
+    /* Set cal with sync and set sync_out and sync_in delay */
+    DDS_WRITE(DDS_USR0, 0x0840 | (sync_delay & 0x3f));
+    DDS_WRITE(DDS_FUD, 0);
+    DDS_WRITE(DDS_CFR4H, 0x0105); /* Enable DAC calibration */
+    DDS_WRITE(DDS_FUD, 0);
+    now += DURATION_DAC_CAL;
+    DDS_WRITE(DDS_CFR4H, 0x0005); /* Disable DAC calibration */
+    DDS_WRITE(DDS_FUD, 0);
+    DDS_WRITE(DDS_CFR1H, 0x0000); /* Enable cosine output */
+    DDS_WRITE(DDS_CFR2H, 0x0080); /* Enable profile mode */
+    DDS_WRITE(DDS_ASF, 0x0fff); /* Set amplitude to maximum */
+    DDS_WRITE(DDS_FUD, 0);
+#endif
+}
+
 /* Compensation to keep phase continuity when switching from absolute or tracking
  * to continuous phase mode. */
 static unsigned int continuous_phase_comp[CONFIG_RTIO_DDS_COUNT][CONFIG_DDS_CHANNELS_PER_BUS];
diff --git a/artiq/runtime/dds.h b/artiq/runtime/dds.h
index 189d9ada7..8cca5cb74 100644
--- a/artiq/runtime/dds.h
+++ b/artiq/runtime/dds.h
@@ -38,6 +38,7 @@
 #define DDS_FTWH   0x2f
 #define DDS_POW    0x31
 #define DDS_ASF    0x33
+#define DDS_USR0   0x6d
 #define DDS_FUD    0x80
 #define DDS_GPIO   0x81
 #endif
@@ -57,6 +58,8 @@ enum {
 };
 
 void dds_init(long long int timestamp, int bus_channel, int channel);
+void dds_init_sync(long long int timestamp, int bus_channel, int channel,
+    int sync_delay);
 void dds_batch_enter(long long int timestamp);
 void dds_batch_exit(void);
 void dds_set(long long int timestamp, int bus_channel, int channel,
diff --git a/artiq/runtime/ksupport.c b/artiq/runtime/ksupport.c
index b881b4f04..d11511bfb 100644
--- a/artiq/runtime/ksupport.c
+++ b/artiq/runtime/ksupport.c
@@ -121,6 +121,7 @@ static const struct symbol runtime_exports[] = {
 
 #if ((defined CONFIG_RTIO_DDS_COUNT) && (CONFIG_RTIO_DDS_COUNT > 0))
     {"dds_init", &dds_init},
+    {"dds_init_sync", &dds_init_sync},
     {"dds_batch_enter", &dds_batch_enter},
     {"dds_batch_exit", &dds_batch_exit},
     {"dds_set", &dds_set},