diff --git a/conda/artiq/meta.yaml b/conda/artiq/meta.yaml
index dec979308..9a2a3daec 100644
--- a/conda/artiq/meta.yaml
+++ b/conda/artiq/meta.yaml
@@ -27,13 +27,13 @@ build:
 
 requirements:
     build:
-        - python
+        - python >=3.4.3
         - setuptools
         - numpy
         - migen
         - pyelftools
     run:
-        - python
+        - python >=3.4.3
         - llvmlite-or1k
         - scipy
         - numpy
diff --git a/setup.py b/setup.py
index ff98ab0ba..b783092fb 100755
--- a/setup.py
+++ b/setup.py
@@ -1,7 +1,10 @@
 #!/usr/bin/env python3
 
 from setuptools import setup, find_packages
+import sys
 
+if sys.version_info[:3] < (3, 4, 3):
+    raise Exception("You need at least Python 3.4.3 to run ARTIQ")
 
 requirements = [
     "sphinx", "sphinx-argparse", "pyserial", "numpy", "scipy",